HELICOBACTER PYLORI TREATMENT

Infectious Diseases

Multiple Drug Regimens for the Treatment of H. pylori Infection

Drug

Dosages

Duration of Therapy

H2-receptor antagonist1

Any one given at appropriate dose

4 weeks

plus

 

 

Bismuth subsalicylate

525 mg 4 times/day

2 weeks

plus

 

 

Metronidazole

250 mg 4 times/day

2 weeks

plus

 

 

Tetracycline

500 mg 4 times/day

2 weeks

Ranitidine bismuth citrate

400 mg twice daily

2 weeks

plus

 

 

Clarithromycin

500 mg twice daily

2 weeks

plus

 

 

Amoxicillin

1000 mg twice daily

2 weeks

Ranitidine bismuth citrate

400 mg twice daily

2 weeks

plus

 

 

Clarithromycin

500 mg twice daily

2 weeks

plus

 

 

Metronidazole

500 mg twice daily

2 weeks

Ranitidine bismuth citrate

400 mg twice daily

2 weeks

plus

 

 

Clarithromycin

500 mg twice daily

2 weeks

plus

 

 

Tetracycline

500 mg twice daily

2 weeks

Proton pump inhibitor1

Esomeprazole 40 mg once daily

10 days

plus

 

 

Clarithromycin

500 mg twice daily

10 days

plus

 

 

Amoxicillin

1000 mg twice daily

10 days

Proton pump inhibitor1

Lansoprazole 30 mg twice daily
Omeprazole 20 mg twice daily

10-14 days

plus

 

 

Clarithromycin

500 mg twice daily

10-14 days

plus

 

 

Amoxicillin

1000 mg twice daily

10-14 days

Proton pump inhibitor

Lansoprazole 30 mg twice daily
Omeprazole 20 mg twice daily

2 weeks

plus

 

 

Clarithromycin

500 mg twice daily

2 weeks

plus

 

 

Metronidazole

500 mg twice daily

2 weeks

Proton pump inhibitor

Lansoprazole 30 mg once daily
Omeprazole 20 mg once daily

2 weeks

plus

 

 

Bismuth

525 mg 4 times/day

2 weeks

plus

 

 

Metronidazole

500 mg 3 times/day

2 weeks

plus

 

 

Tetracycline

500 mg 4 times/day

2 weeks

1FDA-approved regimen

 

 

 

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